Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Signatures of GVHD and relapse after posttransplant cyclophosphamide revealed by immune profiling and machine learning.

McCurdy, Shannon R; Radojcic, Vedran; Tsai, Hua-Ling; Vulic, Ante; Thompson, Elizabeth; Ivcevic, Sanja; Kanakry, Christopher G; Powell, Jonathan D; Lohman, Brian; Adom, Djamilatou; Paczesny, Sophie; Cooke, Kenneth R; Jones, Richard J; Varadhan, Ravi; Symons, Heather J; Luznik, Leo.

Blood ; 139(4): 608-623, 2022 01 27.

Artigo em Inglês | MEDLINE | ID: mdl-34657151

2.

Genetic testing in severe aplastic anemia is required for optimal hematopoietic cell transplant outcomes.

McReynolds, Lisa J; Rafati, Maryam; Wang, Youjin; Ballew, Bari J; Kim, Jung; Williams, Valencia V; Zhou, Weiyin; Hendricks, Rachel M; Dagnall, Casey; Freedman, Neal D; Carter, Brian; Strollo, Sara; Hicks, Belynda; Zhu, Bin; Jones, Kristine; Paczesny, Sophie; Marsh, Steven G E; Spellman, Stephen R; He, Meilun; Wang, Tao; Lee, Stephanie J; Savage, Sharon A; Gadalla, Shahinaz M.

Blood ; 140(8): 909-921, 2022 08 25.

Artigo em Inglês | MEDLINE | ID: mdl-35776903

3.

HLA informs risk predictions after haploidentical stem cell transplantation with posttransplantation cyclophosphamide.

Fuchs, Ephraim J; McCurdy, Shannon R; Solomon, Scott R; Wang, Tao; Herr, Megan R; Modi, Dipenkumar; Grunwald, Michael R; Nishihori, Taiga; Kuxhausen, Michelle; Fingerson, Stephanie; McKallor, Caroline; Bashey, Asad; Kasamon, Yvette L; Bolon, Yung-Tsi; Saad, Ayman; McGuirk, Joseph; Paczesny, Sophie; Gadalla, Shahinaz M; Marsh, Steven G E; Shaw, Bronwen E; Spellman, Stephen R; Lee, Stephanie J; Petersdorf, Effie W.

Blood ; 139(10): 1452-1468, 2022 03 10.

Artigo em Inglês | MEDLINE | ID: mdl-34724567

4.

A biomarker signature to predict complete response to itacitinib and corticosteroids in acute graft-versus-host disease.

Pratta, Michael; Paczesny, Sophie; Socie, Gerard; Barkey, Natalie; Liu, Hao; Owens, Sherry; Arbushites, Michael C; Schroeder, Mark A; Howell, Michael D.

Br J Haematol ; 198(4): 729-739, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-35689489

5.

Assessment of ST2 for risk of death following graft-versus-host disease in pediatric and adult age groups.

Rowan, Courtney M; Pike, Francis; Cooke, Kenneth R; Krance, Robert; Carpenter, Paul A; Duncan, Christine; Jacobsohn, David A; Bollard, Catherine M; Cruz, Conrad Russell Y; Malatpure, Abhijeet; Farag, Sherif S; Renbarger, Jamie; Liu, Hao; Bakoyannis, Giorgos; Hanash, Samir; Paczesny, Sophie.

Blood ; 135(17): 1428-1437, 2020 04 23.

Artigo em Inglês | MEDLINE | ID: mdl-31972009

6.

Structure-Activity relationship of 1-(Furan-2ylmethyl)Pyrrolidine-Based Stimulation-2 (ST2) inhibitors for treating graft versus host disease.

Yuan, Xinrui; Jiang, Hua; Fu, Denggang; Robida, Aaron; Rajanayake, Krishani; Yuan, Hebao; Wen, Bo; Sun, Duxin; Watch, Brennan T; Chinnaswamy, Krishnapriya; Stuckey, Jeanne A; Paczesny, Sophie; Rech, Jason C; Yang, Chao-Yie.

Bioorg Med Chem ; 71: 116942, 2022 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-35930851

7.

Post-haematopoietic cell transplantation outcomes: why ST2 became a 'golden nugget' biomarker.

Paczesny, Sophie.

Br J Haematol ; 192(6): 951-967, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-32039480

8.

An overview of multiplexed analyses of CAR T-cell therapies: insights and potential.

DePriest, Brittany Paige; Vieira, Noah; Bidgoli, Alan; Paczesny, Sophie.

Expert Rev Proteomics ; 18(9): 767-780, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34628995

9.

ST2/MyD88 Deficiency Protects Mice against Acute Graft-versus-Host Disease and Spares Regulatory T Cells.

Griesenauer, Brad; Jiang, Hua; Yang, Jinfeng; Zhang, Jilu; Ramadan, Abdulraouf M; Egbosiuba, Jane; Campa, Khaled; Paczesny, Sophie.

J Immunol ; 202(10): 3053-3064, 2019 05 15.

Artigo em Inglês | MEDLINE | ID: mdl-30979817

10.

Bcl6 and Blimp1 reciprocally regulate ST2⁺ Treg-cell development in the context of allergic airway inflammation.

Koh, Byunghee; Ulrich, Benjamin J; Nelson, Andrew S; Panangipalli, Gayathri; Kharwadkar, Rakshin; Wu, Wenting; Xie, Markus M; Fu, Yongyao; Turner, Matthew J; Paczesny, Sophie; Janga, Sarath Chandra; Dent, Alexander L; Kaplan, Mark H.

J Allergy Clin Immunol ; 146(5): 1121-1136.e9, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32179158

11.

The IL-33 Receptor/ST2 acts as a positive regulator of functional mouse bone marrow hematopoietic stem and progenitor cells.

Capitano, Maegan L; Griesenauer, Brad; Guo, Bin; Cooper, Scott; Paczesny, Sophie; Broxmeyer, Hal E.

Blood Cells Mol Dis ; 84: 102435, 2020 09.

Artigo em Inglês | MEDLINE | ID: mdl-32408242

12.

Biomarkers for posttransplantation outcomes.

Paczesny, Sophie.

Blood ; 131(20): 2193-2204, 2018 05 17.

Artigo em Inglês | MEDLINE | ID: mdl-29622549

13.

Introduction to a review series on emerging immunotherapies for hematologic diseases.

Paczesny, Sophie; Pavletic, Steven Z; Bollard, Catherine M.

Blood ; 131(24): 2617-2620, 2018 06 14.

Artigo em Inglês | MEDLINE | ID: mdl-29728405

14.

Murine chronic graft-versus-host disease proteome profiling discovers CCL15 as a novel biomarker in patients.

Du, Jing; Flynn, Ryan; Paz, Katelyn; Ren, Hong-Gang; Ogata, Yuko; Zhang, Qing; Gafken, Philip R; Storer, Barry E; Roy, Nathan H; Burkhardt, Janis K; Mathews, Wendy; Tolar, Jakub; Lee, Stephanie J; Blazar, Bruce R; Paczesny, Sophie.

Blood ; 131(15): 1743-1754, 2018 04 12.

Artigo em Inglês | MEDLINE | ID: mdl-29348127

15.

Ex vivo culture of mouse skin activates an interleukin 1 alpha-dependent inflammatory response.

Zhou, Hong-Ming; Slominski, Radomir M; Seymour, Leroy J; Bell, Maria C; Dave, Priya; Atumonye, Joseph; Wright, William; Dawes, Avery; Griesenauer, Brad; Paczesny, Sophie; Kaplan, Mark H; Spandau, Dan F; Turner, Matthew J.

Exp Dermatol ; 29(1): 102-106, 2020 01.

Artigo em Inglês | MEDLINE | ID: mdl-31566815

16.

Donor HLA-E Status Associates with Disease-Free Survival and Transplant-Related Mortality after Non In Vivo T Cell-Depleted HSCT for Acute Leukemia.

Tsamadou, Chrysanthi; Fürst, Daniel; Wang, Tao; He, Naya; Lee, Stephanie J; Spellman, Stephen R; Fleischhauer, Katharina; Hsu, Katharine C; Paczesny, Sophie; Verneris, Michael R; Schrezenmeier, Hubert; Mytilineos, Joannis.

Biol Blood Marrow Transplant ; 25(12): 2357-2365, 2019 12.

Artigo em Inglês | MEDLINE | ID: mdl-31425756

17.

HLA-DQ + CD4 help = graft-versus-tumor effect.

Bidgoli, Alan; Paczesny, Sophie.

Blood ; 139(20): 2999-3000, 2022 05 19.

Artigo em Inglês | MEDLINE | ID: mdl-35587871

18.

Plasma biomarkers of risk for death in a multicenter phase 3 trial with uniform transplant characteristics post-allogeneic HCT.

Abu Zaid, Mohammad; Wu, Juan; Wu, Cindy; Logan, Brent R; Yu, Jeffrey; Cutler, Corey; Antin, Joseph H; Paczesny, Sophie; Choi, Sung Won.

Blood ; 129(2): 162-170, 2017 01 12.

Artigo em Inglês | MEDLINE | ID: mdl-27827824

19.

A core group of structurally similar HLA-DPB1 alleles drives permissiveness after hematopoietic cell transplantation.

Arrieta-Bolaños, Esteban; Crivello, Pietro; He, Meilun; Wang, Tao; Gadalla, Shahinaz M; Paczesny, Sophie; Marsh, Steven G E; Lee, Stephanie J; Spellman, Stephen R; Bolon, Yung-Tsi; Fleischhauer, Katharina.

Blood ; 140(6): 659-663, 2022 08 11.

Artigo em Inglês | MEDLINE | ID: mdl-35609150

20.

Neonatal hyperoxia promotes asthma-like features through IL-33-dependent ILC2 responses.

Cheon, In Su; Son, Young Min; Jiang, Li; Goplen, Nicholas P; Kaplan, Mark H; Limper, Andrew H; Kita, Hirohito; Paczesny, Sophie; Prakash, Y S; Tepper, Robert; Ahlfeld, Shawn K; Sun, Jie.

J Allergy Clin Immunol ; 142(4): 1100-1112, 2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-29253513

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